Oprah Winfrey's Weight Loss Journey With Semaglutide

Oprah opens up about her weight-loss journey with peptides

It is no surprise, Oprah Winfrey has been in the headlines a lot lately. According to USA Today, Oprah has had some major recent PR moments including her 70th birthday coming up next month, unveiling a new painting at the Smithsonian in Washington, DC, and her latest weight-loss success. 


Multiple sources share Oprah's direct quotes using weight-loss medication

USA Today, Today, The Washington Post, and People have published direct quotes and interviews from Oprah openly discussing her use of weight loss peptides. Other common brands of this medication on the market include Wegovy, Ozempic, and Mounjaro. As use of peptides to optimize one's health goals has been the talk of celebrities this year, Practical Peptides is excited to see normalization of peptides like Semaglutide holding a strong message in the media. 


Oprah's weight has been a public struggle for decades

Oprah shares weight has long been the subject of intense scrutiny. While appearing on TODAY on December 14th, 2023, Oprah shares her frustration with her weight has “occupied five decades of space" in her brain, she noted.

Obesity is a disease, she added: "It’s not about willpower — it’s about the brain.” It was then that she “released my own shame about it,” she noted, and was prescribed the weight-loss medication by her doctor.

Winfrey realizing that obesity is a biological condition rather than a matter of willpower is wonderful, said Dr. Roshini Raj. 

In a People cover story, published Wednesday, the media mogul, said she's been "blamed and shamed" constantly over her weight. Oprah said it wasn't until this year that she added weight loss medication to her health regimen, which also includes hiking, eating her last meal at 4 p.m. and drinking a gallon of water a day. 


Oprah sharing her journey makes peptide use a household name

Winfrey has lost her latest weight using a weight-loss drug and with a healthy diet and exercising. She told People the weight-loss medication is just part of her regimen for maintaining a healthy weight.

“I know everybody thought I was on it, but I worked so damn hard. I know that if I’m not also working out and vigilant about all the other things, it doesn’t work for me,” she said.

Oprah opened up about using weight-loss medications ("The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption"), making "making hot water cornbread" for longtime partner Stedman Graham and when she's going to retire – which doesn't sounds like it's happening anytime soon. "I will never be done until my last breath is done," she said. "And whenever that happens it will be a peaceful breath."

If you're struggling to lose weight and improve your overall health, Semaglutide might just be the game-changer you've been looking for

This revolutionary treatment has been shown to promote weight loss, improve heart health, and even reduce the risk of certain cancers.

Semaglutide is a GLP-1 receptor agonist, which means it works by mimicking the effects of the hormone GLP-1, which helps to regulate blood sugar levels and reduce appetite.

There are numerous benefits of adding Semaglutide into your regular healthy habits, including promoting weight loss, improving heart health, and reducing the risk of certain cancers. Read all about the latest research on Semaglutide in our resources section. 

How can I start using Semaglutide?

If you are new to Practical Peptides, we have four simple steps in getting started. 

Step 1: Purchase your peptide on www.practicalpeptides.com 

Step 2: Book your virtual consult. 

Step 3: After your virtual consult is complete, we will ship your order to your home. 

Step 4: Watch our tutorial on how to use our peptide therapy. Reach out if you have any questions.

Semaglutide is affordable and accessible for everyone 

Shop our weight loss focused peptides, including Semaglutide and Tirzeptide

Assess your hormones and discover the secrets to weight loss with our Weight Loss Panel.

Have a question about using peptides? Reach out to our experts in the chat on the bottom righthand side of your screen or send us an email

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